Medicinal chemistry

This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more.

This book explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical uses.

As 2019 has been declared the International Year of the Periodic Table, it is appropriate that Structure and Bonding marks this anniversary with two special volumes.

This book highlights the advances in essential oil research, from the plant physiology perspective to large-scale production, including bioanalytical methods and industrial applications.

Latest research on Adhesion GPCRs has unearthed surprising revelations about the events that govern the signal transduction of these receptor molecules and the cellular and organ requirements for these signals.

Medicinal chemistry is both science and art.

This installment in the Techniques in Life Science and Biomedicine for the Non-Expert series aims to describe ESR spectroscopy as a tool for different applications, such as Healthcare & Pharmaceutical Science, Paleontology & Geochronology and Food Science.

This thesis reports studies on the substrate specificity of crucial ketosynthase (KS) domains from trans-AT Polyketide Synthases (PKSs).

This monograph covers a novel technology to deliver drugs and cosmetics through the skin in a minimally invasive manner.

Synthetic chemistry plays a central role in many areas of chemical biology; utilising recent case studies, the goal of Chemical and Biological Synthesis is to highlight the full impact that the preparation of novel reagents can have in chemical biology.

Main Question: G protein coupled receptors are involved in highly efficient and specific activation of signalling pathways.

This volume reviews the recent advances in formation of C-F bonds and X-F bonds (X = heteroatom) to produce useful fluorinated molecules for pharmaceuticals, materials and more.

This book targets new advances in areas of treatment and drug delivery sciences for Malaria.

This book is a volume in the series Topics in Heterocyclic Chemistry.

This volume details applications in molecular biological techniques and focuses on applications to determine the involvement of glycans in virus interactions.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This is an introductory statistics book designed to provide scientists with practical information needed to apply the most common statistical tests to laboratory research data.

The main theme of Part B is the description of synthetically useful reactions and the illustration of their application.

This book explores efficient syntheses of indole alkaloids based on gold-catalyzed cascade cyclizations, presenting two strategies for total synthesis of these natural products based on gold-catalyzed reactions of conjugated diyne or ynamide.

This up-to-date and unique monograph covers the different aspects of pharmaceutical validation, calibration, qualification and documentation.

This book comprehensively reviews the recent developments of natural polymers for drug delivery systems in various lung disorders.

This book presents three types of synthetically cooperative DNA recognizing assemblies, in order to advance the development of programmable DNA-binding pyrrole-imidazole polyamides (PIPs).

This book gives an overview of pharmacoproteomics and its clinical applications, as well as the latest information on drug mechanisms at the proteome level, the relationship between proteomics and toxicity or resistance, and how proteomics aid in discovery of new drug targets.

This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development.

Research in the pharmaceutical industry today is in many respects quite different from what it used to be only fifteen years ago.

The probability for exposure to damaging radiation, toxic chemicals in the environment and adverse biological agents has increased exponentially today.

Medicinal chemistry is both science and art.

This detailed book focuses on analytical separations by chromatographic and electrophoretic techniques, providing some overview along with numerous practically-oriented applications of the most important analytical techniques in chiral separation sciences.

This SpringerBrief provides an overview of ultrasonic emulsification and an update on recent advances in developing stable emulsions for the creation of novel drugs and functional foods, with a focus on bioactive delivery in these products.

This book summarizes the emerging trends in the field of antibiotic resistance of various gram-negative and gram-positive bacterial species.

This book explores the role of nanotechnology in the delivery of natural phytoconstituents and cosmeceuticals.

This book provides the reader with a comprehensive understanding of oral biochemistry by explaining the role of basic biochemistry and dentistry concepts and identifying their metabolic processes of soft tissues that comprise oral and maxillofacial anatomy.

This book volume provides complete and updated information on the applications of Design of Experiments (DoE) and related multivariate techniques at various stages of pharmaceutical product development.

The book offers a comprehensive overview of the unit operations involved in the manufacturing process of solid and liquid dosage forms, along with the scale-up of each operation.

This book has been assembled with the hope of being an authoritative, comprehensive, conceptually sound and highly informative compilation of recent advances describing the concepts of bioengineering in the field of microbiology.

Licorice (Glycyrrhiza) is one of the most widely used in foods, herbal medicine and one of the extensively researched medicinal plants of the world.

The book Function-oriented bioengineered skin equivalents -  continuous development towards complete skin replication aims to provide potential readers with a comprehensive summary of the available information on various in vitro skin models, from historical background to different modeling approaches and their applications.

The book covers the basics of microfluidics, current applications in areas such as formulation, drug delivery, drug screening and development, monitoring and diagnostics, and case studies from a teaching perspective to undergraduate and postgraduate students, allowing application of the content in a flipped classroom.

Drug repurposing, or drug repositioning, or reprofiling, has emerged as a valid approach in modern drug discovery.

Early anthropological evidence for plant use as medicine is 60,000 years old as reported from the Neanderthal grave in Iraq.

This Brief discusses aspects of the increasingly complex production of legal and reliable food products of non-animal origin.

The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research.

In this book, a summary and update of the most important areas of CPP research are presented, whilst  raising relevant questions for further development.

This book outlines how advances in the diverse scientific and engineering disciplines of synthetic biology, DNA synthesis, production of protein therapeutics, and bioinformatics have led to the commercialization of new complex biotherapeutic modalities in modern era, including monoclonal and multi-specific antibodies, antibody drug conjugates (ADC), fusion proteins, CAR-T and CRISPR technologies and applications, mRNA vaccines and more.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

Medicinal chemistry is both science and art.

Serine proteases play significant roles in healh and human disease.

This book is the first of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality.

The second edition of this book has drawn heavily on the first edition but a huge amount of research on steroid analysis has been published over the last 15 years.